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  • Colloid Metrix - Particle Size - NANO-flex® II

    Colloid Metrix – Particle Size – NANO-flex® II

    The NANO-flex® II 180° DLS system measures particle size distributions of suspensions and emulsions in the range of 0.3 nm to 10 μm and concentrations up to 40 % by volume. The principle of heterodyne 180° backscattering applied here is charac…

    The NANO-flex® II 180° DLS system measures particle size distributions of suspensions and emulsions in the range of 0.3 nm to 10 μm and concentrations up to 40 % by volume. The principle of heterodyne 180° backscattering applied here is characterized by its high selectivity in the nm range and a very high resolution; it is also suitable for samples with a wide or multi-modal size distribution. Due to the low penetration depth of the laser light, samples of high concentration are measured without disturbing multiple scattering. Compared to cuvette based systems, many samples can be measured without dilution in original concentration. The dip-in probe used in the NANO-flex® II has a diameter of 5.5 mm and allows a wide range of applications. In conjunction with the IPAS extension, particle size distributions can be measured inline. In combination with the Stabino® II, stability ranges and critical coagulation points can be determined.

  • Particle Metrix - ZetaView

    Particle Metrix – ZetaView

    Biological nanoparticles such as extracellular vesicles (EVs), exosomes, viruses, or virus-like particles are a rapidly growing area of research in the life sciences and nanomedical field. The rapid in vitro measurement of multi…

    Biological nanoparticles such as extracellular vesicles (EVs), exosomes, viruses, or virus-like particles are a rapidly growing area of research in the life sciences and nanomedical field. The rapid in vitro measurement of multiple physical parameters such as size, concentration, surface charge, and phenotype characteristics is the special feature of the Particle Metrix ZetaView®.

    Nanoparticle Tracking Analysis (NTA) captures the Brownian motion of each particle in the video. Based on the different diffusion movements of large and small particles in the surrounding liquid, the hydrodynamic diameter of the particles is determined. Furthermore, the charge state of the particle surface (zeta potential) can be measured via the movement of the particles in an applied electric field.

    Pattern parameters, such as intensity fluctuations, surface geometry and shape of the particles as well as particle concentration are documented at each recording and can be used to distinguish sub-populations.

    All these analyzes are carried out quickly and statistically reliably as required in the scattered light or fluorescence mode.

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